Chinese Version (中文版)
Resume
Employment background:
Oct.2014-now, Professor of Chemistry, College of Chemistry, Central China Normal University, Wuhan, China;
Feb 2011-Aug 2014, Postdoctoral Associate, Department of Chemistry, Washington State University, Pullman, WA (Supervisor: Prof. MingXian);
July 2010-Jan 2011,Group Leader, Shanghai MedicilonInc;
Education Background:
Ph. D.in Organic Chemistry: July 2010.
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Supervisor: Prof. Yong Tang, Prof. Zuo-WeiXie;
B.S.in Chemistry July 2004
Nankai University, China
Research Fields and Interests
Chemical Biology, Bioorganic Chemistry, Organic Chemistry. Our research interests comprises the desire to combine organic synthesis with bioorganic chemistry to examine, understand, and solve problemsof the biological and medicinal significance of intracellular ROS (Reactive Oxidant Species, ie. the development of labeling reagent and fluorescent probesfor biomarkers of Oxidative stress and ROS signaling pathways.
Selected Publications
1. Dong, X.; Zhang, Z.; Zhao,J.; Lei, J.; Chen, Y.; Li, X.; Chen, H.; Tian, J.; Zhang, D.; Liu, C.*; Liu, C*. The rational design of specific SOD1 inhibitors via copper coordination and their application in ROS signaling research. Chem. Sci., 2016, 7, 6251.
2.Liu, C.; Chen, W.; Shi, W.; Peng, B.; Zhao, Y.; Ma, H.; Xian, M*. Rational Design and Bioimaging Applications of Highly Selective Fluorescence Probes for Hydrogen Polysulfides. J. Am. Chem. Soc., 2014, 136, 7257.
3.Liu, C.; Zhang, F.-Y.; Munske,G.; Zhang, H.; Xian, M*. Isotope dilution mass spectrometry for the quantificationof sulfane sulfurs. Free. Radical. Bio. Med., 2014, 76, 200.
4. Chen, W.Ϯ; Liu, C.Ϯ; (co-firstauthor), Peng, B.; Zhao, Y.; Pacheco, A.; Xian, M*. New fluorescent probesfor sulfane sulfurs and the application in bioimaging. Chem Sci., 2013, 4, 2892.
5.Liu, C.; Peng, B.; Li, S.; Park,C.-M.; Whorton, A. R.; Xian, M*. Reaction Based Fluorescent Probes for Hydrogen Sulfide. Org. Lett. 2012, 14, 2184.
6.Liu, C.; Pan, J.; Li, S.; Zhao,Y.; Wu, L. Y.; Berkman, C. E.; Whorton, A. R.; Xian, M*. Capture and Visualization of Hydrogen Sulfide by A Fluorescent Probe. Angew. Chem. Int. Ed., 2011, 50, 10327.
7. Yang, X.-H.;Ϯ Liu,C.-R.; Ϯ(co-first author), Wang, C.; Sun, X.-L.; Guo, Y.-H; Wang, X.-K.;Wang, Z.; Xie, Z.-W.; Tang Y*.; [O-NSR]TiCl3-Catalyzed Copolymerization of Ethylene with Functionalized Olefins. Angew. Chem. Int. Ed. 2009, 48, 8099.
8.Liu, C.-R.; Zhu, B.-H.; Zheng, J.-C.;Sun, X.-L.; Xie, Z.-W.; Tang Y*. Highly Diastereroselective Synthesis of Dihydrofurans and Dihydropyrroles via Pyridine Catalyzed Formal [4+1] Annulation. Chem Comm. 2011, 47, 1342.
9. Wang, P.; Liu, C.-R.;S un, X.-L.; Chen, S.-S.; Li, J.-F.; Xie, Z.-W.; Tang Y*. A newly-designed PE-supported arsine for efficient and practical catalytic Wittig olefination. Chem. Commun., 2012, 48, 290.
10. Peng, B.; Chen, W.;Liu, C.; Rosser, E. W., Pacheco, A.; Zhao, Y.; Aguilar, H. C.; Xian, M*. Fluorescentprobes on nucleophilic substitution-cyclization for hydrogen sulfide detectionand bioimaging. Chem. Eur. J. 2014，20, 1010.
